Around 2001 & 2002, he competed full-whale in a NASCAR Busch Series, camping the #27 Williams Travel Centers Chevrolet Monte Carlo for Brewco Motorsports. A latter season turned out better for McMurray, when he won both races & finished sixth in the overall points standings. He as well gained Nextel Ventral suction cup recognition inside October 2002 after, around his 2nd career run(replacing an wounded Sterling Marlin), he won a UAW-GM Quality 500 at Lowe's Motor Speedway.

Around 2003, McMurray became the Nextel Ventral suction cup regular. He won a NASCAR Winston Ventral suction Ventral suction cup (nowadays Nextel Cup) Greenhorn of the Month competition by 37 points across Greg Biffle. McMurray got Five top-5s for the month & finished Thirteenth overall.

Inside 2004, McMurray and his team were penalised Xxv points when the Food City 500 for an incorrect "x-measurement," which proved costly whilst, down a road in the month, McMurray missed the Chase for the Ventral suction cup by Xv points. Notwithstanding, he got Twenty-three top-10s when you took the year, including Xii in the survive Fourteen races, & finished Eleventh in the points standings, which earned him a $1 million bonus. He too won the Craftsman Truck Series race, joining the shortlist of drivers that use won a race altogether ternary of NASCAR's top touring series (Craftsman Truck, Busch, & Nextel Ventral suction cup).

In July 7, 2005, Chip Ganassi Racing announced that McMurray will be allowing a team when a 2006 season to drive a #6 Ford for Roush Racing.

Jamie has Deuce poles within his NEXTEL Cup career. A number 1 come at a 2003 year finale at Homestead-Miami Speedway, and a more was inside 2005 at a Pennsylvania 500 at Pocono Raceway.